(Inject able Version is + Enanthate Ester)
Chemical Name:17beta-Hydroxy-1-methyl-5alpha-androst-1-en-3-one, 1-methyl-1(5-alpha)-androsten-3-one-17b-ol
Molecular weight of base: 302.4558
Molecular weight of Acetate ester: 60.0524
Molecular weight of Enanthate ester: 130.1864
Effective dose(oral): (Men)50-100mgs/day; (Women) 10-25mgs/day
Effective dose (inject able): (Men) 350-600mgs/week; (Women) 100mgs/week
Active Life: 10-14 days (inject able); 4-6hrs (oral)
Detection Time: 4-5 weeks
Primobolan is a well-known and popular steroid as well. Like nandrolone it’s most often used as a base compound for stacking with other steroids. Methenolone however, is a DHT-based steroid (actually, DHB or dihydroboldenone, the 5-alpha reduced of the milder boldenon). Meaning when it interacts with the aromatase enzyme it does not form estrogens at all. That makes it ideal for use when cutting when excess estrogen is best avoided because of its retentive effects on water and fat. Methenolone is mostly only used in such instances, or by people who are very succeptible to estrogenic side-effects, because the anabolic activity of methenolone is slightly lower than that of nandrolone, quite likely BECAUSE it is non-estrogenic.
Because it is a widely available steroid its often used as a replacement for nandrolone or boldenone to those who have no access to Deca-Durabolin or Laurabolin or Equipoise. When stacked with a heavy mass steroid like testosterone and/or methandrostenolone it can deliver almost similar gains. Those seeking to cut will most likely be very pleased stacking it with drostanolone, stanozolol or trenbolone. Women and beginners also stack methenolone WITH nandrolone because this gives a mildly anabolic stack that is generally regarded as one of the safer stacks around in an androgenic perspective. But alas, with the nandrolone, also a very suppressive stack.
Methenolone is available as an injection or as an oral. The injection is naturally regarded as better. Its an enanthate ester which is quite long-acting and only needs to be injected once a week in doses of 300-600 mg. Because it by-passes hepatic breakdown on the first pass, it also has a higher survival rate. The orals are a lot less handy, but often preferred by bodybuilders who are afraid of needles or who are already taking one or more inject able compounds. The tabs are in a short-lived acetate form, meaning that doses of 100-150 mg per day are needed, split over 2 or 3 doses, making the tabs quite inconvenient for use. The reason doses need to be split up, unlike most oral steroids, is because Methenolone is not 17-alpha-alkylated, but 1-methylated for oral bio-availability. This reduces the liver stress, but also the availability, hence the multiple and high doses needed daily.
Like nandrolone, methenolone is very mild on the system. Probably the reason why both are strongly favored as base compounds in stacks. Methenolone has no estrogenic side-effects whatsoever, on account of its structure. Its effects on the cholesterol levels are barely noticeable. In doses of 200 mg or less (injectable) blood pressure is rarely, if at all, altered. As for hepatoxicity, long-term use will of course increase liver values but gradually and only slightly. The injections of course, since they only pass the liver once, have roughly half the liver-toxic effects of the tabs. The low liver-toxicity is accounted for that the bio-availability of methenolone is carried by a 1-methyl-group, which lessens the need for a carrier attachment such as a 17-alpha-akylated group, the main culprit in steroid-related liver afflictions.
The strangest thing however, taking into account that Primo is still a DHT (or rather DHB) derivative, is that it is quite easy on the system androgenically as well. Women use methenolone often, usually the tabs, and find little virilisation symptoms in short term use of methenolone. Long-term use may induce some acne and a deepening of the voice however. Methenolone is also not overly suppressive of the HPT axis (endocrinal axis for the production of natural testosterone). These are both the result of DHB’s 1,2-double bond, which, analog to the parent structure boldenone, reduces the androgenic binding by 50% as opposed to DHT.
For athletes who wish to maintain a “natural” status in competition, the tablets are quite well-suited as detection chances for the acetate-form are quite slim. However tests have improved and quite a number of metabolites1 of methenolone can be detected with a simple urine sample. But an English study documented that there is a liability in eating methenolone contaminated meats2, which could provide a possible defense if found out. One could always claim they ate the meat of a chicken or cow injected with methenolone since the test concluded eating such meat does not improve performance, but can deliver positive tests for several methenolone metabolites almost 24 hours after ingestion. That’s for those of you seeking a viable defense against a possible methenolone-positive.
Primobolan is a registered trademark of Schering A/G avaiable in 50 mg/cc from Mexico and 100 mg/cc from Europe. It is is the “Cleanest and Gentles” anabolic steroid, will not aromatize, non-toxic, low in androgens.
Primobolan may be taken by both Men and Women. Dosages for men are 100-300 mg/week, Women 1/2 dosage. Primobolan is the only steroid that works well on a low calorie diet. Effective for bulking, but tends to harden and add muscle tone more that build big muscles.
Primobolan works great when added to a cycle (stacked) with other steroids, it tends to lessen water retention and harshness when stacked with more heavy duty testosterone injectables, like Omnadren / Sustanon, Cypoinate / Propionate, ect. It is an analog immune-stimulating steroid used by people with Aids and others with depressed immune systems to build up the immune system and add lean muscle mass. Primobolan is one of the finest steroids in the world today
by Bill Roberts – Primobolan is a Class I steroid working well at the androgen receptor but which apparently is ineffective in non-AR-mediated anabolic effects. It is most closely compared to Deca Durabolin , requiring a little higher dosage to achieve the same anabolic effect, but since it is pleasant to use at doses considerably higher than what is pleasant for nandrolone esters, it can achieve higher maximal effectiveness. That is, provided that one can afford it a gram per week of Primobolan can be costly. 400 mg/week should be considered a reasonable minimum dose.
It appears to cause less inhibition than Deca or testosterone for any given degree of anabolic effect, perhaps because of low CNS activity, lack of conversion to DHT, and lack of aromatization to estrogen. Unlike Deca, it is not metabolically deactivated by 5a-reductase and therefore is not as kind to the skin and hair as that drug. However, when used by itself at modest doses, by suppressing natural testosterone and DHT production, it can improve skin relative to using no anabolic steroids at all.
The half-life is probably about 5 days.
The drug is particularly excellent for use as the last injectable used in a cycle, since for any given anabolic effect it gives much less inhibition than other steroids such as testosterone, nandrolone, or trenbolone . Therefore, residual levels of Primobolan can allow recovery in the taper while still offering useful anti-catabolic or even anabolic support.
hemical Characteristics of Primobolan
Primobolan is a Dihydrostestosterone (DHT) derivative, landing it in the family of DHT-derivatives and analogues. Primo is a modified form of DHT, where it contains a double-bond between carbon atoms 1 and 2 in the Dihydrotestosterone structure. This is known to assist in the stabilization of the 3-keto group which in turn increases the anabolic strength of the hormone. A 1-methyl group is also added to the hormone, which is responsible for allowing the hormone to resist hepatic (liver) metabolism and breakdown.
The oral format of Primobolan holds an Acetate ester chemically bonded to it, which is attached to the 17-beta-hydroxyl group on the chemical structure. This allows the oral anabolic steroid to be resistant to oxidation and hepatic breakdown through oral administration. The oral form of Primobolan has demonstrated effective oral bioavailability in studies as both in its Acetate format as well as its un-esterified format . Esterification will now be explained in more detail.
The injectable format (Methenolone Enanthate) in particular is simply Methenolone with the Enanthate ester bound to the Methenolonechemical structure. Specifically, ‘Enanthate’ is Enanthoic acid (also known as carboxylic acid), but once bound to Methenolone it is properly referred to in chemistry as an ester bond (or ester linkage). Enanthoic acid is chemically bonded to the 17-beta hydroxyl group on the Methenolone structure. The addition of this ester augments the hormone’s release rate and half-life to favor a longer window of release. The primary reason for the augmentation of its half-life and release rate is because once Methenolone Enanthate enters the bloodstream, enzymes work to break the bond between the ester and the hormone, which takes a varying amount of time. The end result is that of the ester being removed from the hormone by these enzymes, and the result after this is pure Methenolone that is free to do its work in the body. This process of enzymes removing the ester from the hormone to which it is attached is what is responsible for the slower release rates. When the Enanthate ester is attached to Methenolone, creating Methenolone Enanthate, the half-life of Primobolan is now extended to 10 days, providing a slower release and activity of the hormone.